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Chapter 4Pilot trial Objectives The pilot trial aimed to assess the feasibility of a main trial and to test all trial procedures.

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As this was a behavioural intervention unlikely to cause harm there were no stopping rules. See how your data is managed We could not reach one participant at the provided. Apple disclaims any and all liability for the acts, omissions and conduct of any third parties in connection with or related to your use of the site. The messages were deed to phonr social support for safer sexual behaviours.

Can text messages increase safer sex behaviours in young people? Intervention development and pilot randomised controlled trial.

Nonetheless, as the primary outcomes for the pilot were recruitment and follow-up, the allocation balance would not impact on this. The intervention for negative male participants consisted of 49 text messages, starting from the point of randomisation. Participants who had not been diagnosed with an infection were sent the messages about safer sexual behaviours condom use and testing for STI starting on day 1. For those diagnosed with an infection, after day 14 chat free boy messages targeted condom use and testing for STIs before having unprotected sex with a new partner, employing the same messages as for those who were not diagnosed with an infection.

Adjustments for covariates We did not adjust for covariates in the primary analysis. Chapter 4Pilot trial Objectives The pilot trial aimed to assess the feasibility of a main trial and to test all trial procedures.

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Recruitment We identified participants from seven sexual health services located in inner-city Manchester, south-east London, Cambridgeshire, Norfolk, Maidstone, Hull and London Brook services. All participants including participants randomised sxe the intervention received the control messages. Laboratory staff assessing chlamydia infection and researchers assessing the outcomes were masked to treatment allocation. Multiple comparisons We did not adjust for multiple comparisons.

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Research staff recruited participants on site at the London and Manchester services. Strengths and weakness In the pilot trial we achieved a high follow-up rate, allocation was concealed and laboratory staff and those analysing data were blind to allocation. There were some differences in baseline infections and ethnicity between groups. Outcomes Primary outcomes The primary outcomes for the pilot trial were the recruitment rates and completeness of follow-up for the proposed primary outcome for the main trial cumulative incidence of STIs at 12 months.

Interim analyses and stopping rules There were no interim analyses. If the infection status was pending, recruiting staff entered the baseline data as soon as they received the test result from the laboratory usually within 1 week. The set of moving to wayne seeking texting friends messages consisted of 13 messages in total, which were spaced 30 days apart starting from the point of randomisation see Table 6.

The computer automated mode of delivery ensured standardisation of the intervention. Participants were also sent links to further web-based information regarding contraception, alcohol and sexual risk, how to use a condom and general communication about sex.

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Baseline demographic and sexual behaviour characteristics Primary outcomes Our primary outcomes were full recruitment within 3 months and follow-up rate for our trxt primary outcome for the main trial. The intervention for positive male participants consisted of 61 text messages sent over 1 year, starting from the point of randomisation.

Participants were randomised from 9 Phome to 29 November and were followed up between October and the end of February Data were double entered with one researcher masked to allocation. Control Control messages were also delivered through the bespoke texting software, that is, during the chosen non-embargoed time period.

Data collection and entry We collected self-reported data using the trial baseline and follow-up questionnaires.

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OM telephoned nnumbers referrals and provided detailed verbal information. Participants who were enrolled by telephone referral provided baseline data to OM over the telephone. The width of the CI was calculated by 1. Methods Description of trial de This was a pilot, parallel-arm randomised controlled trial with an allocation ratio of 1 : 1, conducted in multi-geographical areas of the UK. Over the next week messages targeted telling partner s about an infection.

Staff at other services identified eligible participants aged 16—24 years and who had recently received a positive chlamydia test result and asked those who were interested in participating for their permission to pass their mobile phone to OM. Recruitment staff recruited participants on site at the service or staff referred eligible participants to OM at LSHTM for telephone recruitment.

People who satisfied these requirements were ineligible if they were non-English-language speakers or were unable to numberrs informed consent e. All postings and use of the content on this site are subject to the Apple Support Communities Terms of Use.

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Messages provided information about how to prevent infections. The messages numberd non-judgemental, non-stigmatising information covering how common infections are, that an individual may not have symptoms and so therefore be unaware that they have a STI; that many people diagnosed with a STI have had only one sexual partner in the year, and that infections are easy to treat.

Discussion Key findings The pilot trial demonstrated the feasibility of the trial procedures for a main trial. Phlne total, 99 participants were native american bellingham to the intervention and were allocated to the control see Figure 1. Two mobile phone s went straight to voic, two s were not in service and we could not reach one participant at the provided.

The of messages was then reduced to one per day for the first month followed by between one and nine per month until 12 months. Settings and locations where the data were collected This trial identified potential participants through sexual health services in six geographical locations in the UK: London, Cambridgeshire rural and urbanManchester, East Anglia, Kent and Sexx.

Our response rate may be higher than that achieved by the ClaSS project because our participants had agreed to provide follow-up data when they were recruited, we offered unconditional incentives and we included only essential test kit components.

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The intervention has been deed to be accessible across socioeconomic and ethnic groups. Three mobile phone s went straight to voic and two s were numbesr in service after many attempts. One participant returned the month 3 test kit only positive test result but withdrew around 7 months after randomisation. The treatment allocation variable in the data set was coded 1 or 2 and this was kept undisclosed until the full analysis was complete.

We assessed the follow-up response by the s completing the questionnaire at months 1 and 12 and returning a chlamydia test sample at months 3 frostburg phone chat free The message set was tailored according to sex and infection status at enrolment no infection, chlamydia, gonorrhoea or NSU.

Women were sent messages covering how other women had negotiated condom use.

Recruitment stopped once we had achieved our target recruitment. About one-fifth of respondents thought that there were too many messages and test one-fifth thought there were too few.